|本期目录/Table of Contents|

[1]陈梅,张锋,明津法,等.静电纺丝素-透明质酸共混纳米纤维形态结构研究[J].丝绸,2012,49(06):000005-7.
 CHEN Mei,ZHANG Feng,MING Jin-fa,et al.Study on electrospun Silk Fibroin-Hyaluronic acid blends nanofbers and its structure[J].Journal of Silk,2012,49(06):000005-7.
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静电纺丝素-透明质酸共混纳米纤维形态结构研究(PDF)
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《丝绸》[ISSN:1001-7003/CN:33-1122/TS]

卷:
49
期数:
2012年06期
页码:
000005-7
栏目:
研究与技术
出版日期:
2012-06-20

文章信息/Info

Title:
Study on electrospun Silk Fibroin-Hyaluronic acid blends nanofbers and its structure
文章编号:
1001-7003(2012)06-0005-03
作者:
陈梅12a张锋2b明津法12a高艳菲12a左保齐12a
1.现代丝绸国家工程实验室,江苏 苏州 215123;2.苏州大学 a. 纺织与服装工程学院;b. 基础医学与生物科学学院,江苏 苏州 215123
Author(s):
CHEN Mei 12a ZHANG Feng 2b MING Jin-fa 12a GAO Yan-fei 12a ZUO Bao-qi 12a
1.National Engineering Laboratory for Modern Silk, Suzhou 215123, China; 2a.College of Textile and Clothing Engineering; 2b.School of Biology & Basic Medical Sciences, Soochow University, Suzhou 215021, China
关键词:
丝素蛋白透明质酸静电纺丝共混纳米纤维
Keywords:
Silk fibroin Hyaluronic acid Electrospun Blend nanofibers
分类号:
TB383
doi:
-
文献标志码:
A
摘要:
以甲酸为溶剂,采用静电纺丝方法制备丝素蛋白(SF)与不同相对分子质量的透明质酸(HA)共混纳米纤维,并通过扫描电镜(SEM)、红外光谱(FTIR)、X射线衍射(XRD)和热分析(TG-DTA) 研究了SF-HA共混纳米纤维非织造网的形态、结构和性能。结果表明:通过静电纺丝,丝素与低分子量的透明质酸共混纳米纤维直径在100 nm左右,纤维表面光滑,呈圆柱状;高分子量透明质酸的加入使得纤维形态变差,出现严重的粘连现象;透明质酸的加入未对丝素分子构象和结晶结构产生明显影响。
Abstract:
Silk fibroin and different molecular hyaluronic acid blend nanofibers (SF-HA) were obtained by electro spinning and using formic acid as solvent. Morphological structure and molecular structure of the SF-HA blend nanofibers were examinedby SEM, FTIR, XRD, TG-DTA. It shows that the average diameters of SF-HA blend nanofibers was about 100 nm; the surface of blend fibers was smooth and the shape was cylindrical; with the addition of high molecular hyaluronic acid, the morphology of SF-HA became worse and the nanofibers had serious connection with each other. However, the result proved that the addition of little hyaluronic acid had no significant effect on the molecular conformation and crystal structure.

参考文献/References:

[1]ROCKWOOD D N, PREDA R C, YÜCEL T, et al. Materials fabrication from Bombyx mori silk fibroin[J]. Nature Protocols, 2011, 6: 1612-1631.
[2]HARDY J G, SCHEIBEL T R. Composite materials based on silk[J]. Prog Polym Sci, 2010, 35: 1093-1115.
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[4]周文,陈新,邵正中.红外和拉曼光谱用于对丝蛋白构象的研究[J].化学进展,2006,18(11):1514-1522.
ZHOU Wen, CHEN Xin, SHAO Zhengzhong. Conformation Studies of Silk Proteins With Infrared and Raman Spectroscopy Progress in Chemistry[J]. Progress in Chemistry, 2006, 18(11): 1514-1522.
[5]LI M Z, WU Z Y, LU S Z, et al. Study on porous silk fibroin materials[J]. Journal of Dong Hua University, 2001, 27(2): 12-19.
[6]LI M Z, LU S Z, WU Z Y, et al. Study on porous silk fibroin materials: fine structure of freeze-dried silk fibroin[J]. J Appl Polym Sci, 2001, 79: 2185-2191.
[7]HU X, LU Q, SUN L, et al. Biomaterials from ultrasonicationinduced silk fibroin-hyaluronic acid hydrogel[J]. Biomacromolecules, 2010,11: 3178-3188.

备注/Memo

备注/Memo:
收稿日期:2011-11-29;
修回日期:2012-01-03
基金项目:苏州市科技计划项目(SG201046);江苏省高校优势学科一期建设工程项目(苏政办发[2011]6号)
作者简介:陈梅(1987- ),女,硕士研究生,研究方向为丝素蛋白生物材料。
通讯作者:左保齐,教授,博导,bqzuo@suda.edu.cn
更新日期/Last Update: 2012-06-27